I was working with customer today which has MySQL on a system with some 64GB or RAM running MyISAM, so they set key_buffer_size to 16G… and every few days MySQL crashes. Why ? Because key_buffer_size over 4GB in size is not really supported (checked with latest and greatest MySQL Enterprise 5.0.34). It works just fine [...]
Getting use of Slave in MySQL Replication
MySQL Replication is asynchronous which causes problems if you would like to use MySQL Slave as it can contain stale data. It is true delay is often insignificant but in times of heavy load or in case you was running some heavy queries on the master which not take time to replicate to the slave [...]

